Tuberculosis (TB) is
an infectious disease usually caused by the bacterium mycobacterium tuberculosis.
It is a serious infectious disease that mainly affects the lungs. This bacteria
is spread from one person to another through tiny droplets released into the
air via coughs and sneezes.
It used to be rare in developed countries, tuberculosis
infections began increasing in 1985, partly because of the emergence of HIV,
the virus that causes AIDS. HIV weakens a person's immune system so it can't
fight the TB germs.
Many strains of tuberculosis resist the drugs most used to treat
the disease. People with active tuberculosis must take several types of
medications for many months to eradicate the infection and prevent development
of antibiotic resistance.
SYMPTOMS
Although your body
may harbor the bacteria that cause tuberculosis, your immune system usually can
prevent you from becoming sick. For this reason, doctors make a distinction
between:
·
Latent TB. In this condition, one has a TB infection, but the
bacteria remain in the body in an inactive state and cause no symptoms. Latent
TB, also called inactive TB is not contagious. It can turn into
active TB, so treatment is important for the person with latent TB and to help
control the spread of TB.
·
Active TB. This is the infectious TB, it shows signs and can spread
to others. It can occur in the first few weeks after infection with the TB
bacteria, or it might occur years later.
Signs and symptoms of
active TB include:
·
Coughing that lasts
three or more weeks
·
Coughing up blood
·
Chest pain, or pain
with breathing or coughing
·
Unintentional weight
loss
·
Fatigue
·
Fever
·
Night sweats
·
Chills
·
Loss of appetite
Tuberculosis can also
affect other parts of the body. Tuberculosis can affect the kidney, spine and
brain. When TB occurs outside the lungs, signs and symptoms vary according to
the organs involved. For example, tuberculosis of the spine may give you back
pain, and tuberculosis in your kidneys might cause blood in your urine.
CAUSES
Tuberculosis is caused by bacteria that spread from person to
person through microscopic droplets released into the air. This can happen when
someone with the untreated, active form of tuberculosis coughs, speaks,
sneezes, spits, laughs or sings.
Although tuberculosis is contagious, it is not easy to catch.
You are much more likely to get tuberculosis from someone you live with or work
with than from a stranger. Most people with active TB who have had appropriate
drug treatment for at least two weeks are no longer contagious
HIV
AND TB
Due to the emergence of
HIV, cases of tuberculosis increased dramatically. Infection with HIV
suppresses the immune system, making it difficult for the body to fight TB
bacteria. As a result, people living with HIV are many times more likely to get
TB and to progress from latent to active disease.
RISK FACTORS
Anyone can get tuberculosis, but certain factors can increase
your risk of the disease. These factors include:
Weakened immune
system
A healthy immune system often successfully fights TB bacteria,
but a weak immune system won’t be able to fight germs and bacteria. A number of
diseases and medications can weaken your immune system, including:
·
HIV/AIDS
·
Diabetes
·
Severe kidney disease
·
Certain cancers
·
Cancer treatment,
such as chemotherapy
·
Drugs to prevent
rejection of transplanted organs
·
Some drugs used to
treat rheumatoid arthritis, Crohn's disease and psoriasis
·
Malnutrition
PREVENTION
If you test positive for latent TB infection, your doctor may
advise you to take medications to reduce your risk of developing active
tuberculosis. The only type of tuberculosis that is contagious is the active
variety, when it affects the lungs. So if you can prevent your latent
tuberculosis from becoming active, you won't transmit tuberculosis to anyone
else.
Vaccinations
In countries where tuberculosis is more common, infants often
are vaccinated with bacillus Calmette-Guerin (BCG) vaccine because it can
prevent severe tuberculosis in children.













