Tuesday, 14 March 2017

AUTOIMMUNE DISEASE/DISORDER

An autoimmune disease develops when your immune system, which defends your body against disease, decides your healthy cells are foreign. As a result, your immune system attacks healthy cells. Depending on the type, an autoimmune disease can affect one or many different types of body tissue. It can also cause abnormal organ growth and changes in organ function.



There are as many as 80 types of autoimmune diseases. Many of them have similar symptoms, which makes them very difficult to diagnose. It’s also possible to have more than one at the same time. Autoimmune diseases usually fluctuate between periods of remission (little or no symptoms) and flare-ups (worsening symptoms).
Autoimmune diseases often run in families, and 75 percent of those affected are women.

WHAT CAUSES THE IMMUNE SYSTEM TO ATTACK HEALTHY CELLS?

The exact cause of autoimmune disorders is unknown. One theory is that some microorganisms (such as bacteria or viruses) or drugs may trigger changes that confuse the immune system.
Also, you may be more susceptible to developing an autoimmune disease if you have a family member with one.
SYMPTOMS

Because there are so many different types of autoimmune disease, the symptoms vary. However, common symptoms are fatigue, fever, and general malaise (feeling ill). Symptoms worsen during flare-ups and lessen during remission.
Autoimmune diseases affect many parts of the body. The most common organs and tissue affected are:
·         joints
·         muscles
·         skin
·         red blood cells
·         blood vessels
·         connective tissue
·         endocrine glands


DISGNOSIS

Ordinarily, your immune system produces antibodies (proteins that recognize and destroy specific substances) against harmful invaders in your body. These invaders include:
·         viruses
·         bacteria
·         parasites
·         fungi

When you have an autoimmune disease, your body produces antibodies against some of your own tissues. Diagnosing an autoimmune disease involves identifying the antibodies your body is producing.
The following tests are used to diagnose an autoimmune disease:
·         autoantibody tests: any of several tests that look for specific antibodies to your own tissues
·         antinuclear antibody tests: a type of autoantibody test that looks for antinuclear antibodies, which attack the nuclei of cells in your body
·         complete blood count: measures the numbers of red and white cells in your blood; when your immune system is actively fighting something, these numbers will vary from the normal
·         C-reactive protein (CRP): elevated CRP is an indication of inflammation throughout your body
·         erythrocyte sedimentation rate: this test indirectly measures how much inflammation is in your body

TREATMENT

Autoimmune diseases are chronic conditions with no cure. Treatment involves attempts to control the process of the disease and to decrease the symptoms, especially during flare-ups. The following is a list of things you can do to alleviate the symptoms of an autoimmune disease:
·         eat a balanced and healthy diet
·         exercise regularly
·         get plenty of rest
·         take vitamin supplements
·         decrease stress
·         limit sun exposure
·         avoid any known triggers of flare-ups
Medical interventions include:
·         hormone replacement therapy, if necessary
·         blood transfusions, if blood is affected
·         anti-inflammatory medication, if joints are affected
·         pain medication
·         immunosuppressive medication

PREVENTION

There is no known prevention for most autoimmune disorders, it just occurs and can re stabilize on its own after a period of time. Reoccurrence is eminent in same individual.
Self medication should be avoided due to certain researches has shown drugs aid in autoimmune disorder. Take medications ONLY prescribed by a qualified medical personnel. Tattoos can as well trigger autoimmune disorders for the skin due to chemicals used in the process.

COMMON AUTOIMMUNE DISEASES

(1)  Immune mediated or type 1- Diabetes mellitus
(2)  Multiple sclerosis
(3)  Rheumatoid arthritis
(4)  Inflammatory bowel diseases
(5)  Systemic lupus erythematosus
(6)  Psoriasis
(7)  Scleroderma
(8)  Autoimmune thyroid disease

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